I went back and listened to all when I started frequenting the site. Of course that was a lot less, about 300 less, but I think the majority is worth sitting through. The E3, pre E3 podcasts are often the best ones, but in general they're all pretty amazing. you should go back and listen to the infamous E-shop run. It's great.
I love the fact that you didn't give any indication of what kind of champ you're playing. Heavy strength 2H-greatsword? Magic sword? pyro/sword? pyro/magic? dagger or scimitar? leather armor? havel's armor? what rings? what's the spec?
It'd be like asking how to raid in wow, without ever telling anyone what class you are. Play style is super dependent on that shit.