Does not appear so. Just did some research and looked at the game's announcement information. Also, Gamespot, Wikipedia et al. have it listed as PC, PS4, MAC. I will edit the wiki to reflect until better evidence emerges this will actually launch on Xbox.
And yep, that is one pretty-ass game. (I like butts, this is a sincere compliment) Zero-G environments have been some of my very favourite parts of Sci-Fi video games over the last decade. Dead Space 1 in particular just nailed that sensation of contrasting claustrophobia and wonder.
Also, let's not forget the BioForge Zero G segments. Let's never forget.