Before my 360 got the E73, I had recently finished Bioshock and really enjoyed it. So naturally I'm very excited for Bioshock 2 which should be coming soon.  
 
Another game I have on my mind is Modern Warfare 2, which if I get it, will be my first entry into the Call of Duty series. And it seems like a good time to start:D.   
 
Finally, Brutal Legend. Which is self-explanatory, I love metal, Jack Black kicks ass, I'm all for epic adventure games and hack and slashers, did I mention I love metal?
 
Besides that, I have no other games I'm really excited for. I do want 2 other games which I believe are being released in 2010, Metro 2033 The Last Refuge (post-apocolyptic shooter\survival horror) and Final Fantasy 13 (I'm an FF fan).