So the idea of having a bunch of cities that exist in the same world and affect each other sounds amazing and actually is enough to get me over the always-online complaint. I can imagine how fun it will be to a group that gets to know each other through the cities they build, like everybody starts to hate that guy to the west that keeps sending pollution towards your city, or forming alliances with other players to share resources and not share with others.
Sounds like it can be a really fun multiplayer experience. I don't know the limit for amount of players playing together in a region but I would hope it's a pretty high number to create some really interesting situations.
Who else is pumped for the potential griefing experiences with fellow duders!?