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Dr. Aaron Aikman is The Spider-Man of Earth-31411.
Vulture is a villain in Marvel Comic's Spider-Man Series. Adrian Toomes created the flight suit and became the Vulture.
Agony is a child symbiote of Venom, enemy of Spider-Man.
A spider god in Mochica culture. He became the second Dark Spider-Man in Marvel Comics.
Rhino is a nemesis of Spider-Man. His costume gives him superhuman durability and strength.
Spider-Man villain often associated with Spider-Slayers, along with his father, Spencer Smythe.
The daughter of Peter and Mary Jane Parker in the "Renew Your Vows" storyline.
Anansi is the West African spider god.
Arachne (formerly known as Spider-Woman) is from the Marvel Comics universe.
An in-universe rip-off of Spider-Man in a movie that was being filmed.
A vigilante from Mexico City who took up the name of his luchador father after his death.
Anya Corazon is a teenage superheroine who has gone by the names Araña and Spider-Girl.
Ashley Barton is the daughter of Clint Barton (Hawkeye) and granddaughter of Peter Parker (Spider-Man), commonly known as Spider-Bitch (or in more family-friendly publications, just Spider-Girl).
Spider-Man villain who commits crimes in a flying suit of armor shaped after a beetle.
In the Marvel Universe, Urich is one of the most respected reporters in New York City. He is usually associated with the Daily Bugle.
A friend and coworker of Peter Parker's at the Daily Bugle.
Big Wheel is an enemy in the Spider-Man universe and is featured in the game Spider-Man: Mysterio's Menace.
Black Cat is a sometimes burglar, sometimes hero, friend and former lover of Spider-Man. She gains her abilities from a combination of magic and science.
Genetically altered clone of Black Cat. She has all of Felicia Hardy's memories...and feelings for Spider-Man.
Blood Spider was a disciple of Taskmaster designed to mimic and oppose Spider-Man.
In the Spider-Man movie universe, Bonesaw was Spider-Man's wrestling opponent, before Peter Parker became a super hero.
The killer of Spider-Man's Uncle Ben.
An enemy of Spider-Man, she's a voodoo priestess who constantly brings herself back to life.
Carlie Cooper is a forensic scientist working for the New York City Police Department in the Marvel Universe. She is an ally and one-time girlfriend of Spider-Man.
A merging of the Carnage and Venom symbiotes, created specifically for Lego Marvel Super Heroes 2.
Spider-Man villain. Able to rot flesh with just a touch, Carrion is the result of Dr. Miles Warren's genetic experiments.
The Carnage symbiote is the offspring of the Venom symbiote. Cletus Kassidy is the main host for the Carnage symbiote but it has bounded with others over the years.
Cloak, along with Dagger, is a runaway. They are two lonely teenagers who ran away to New York City to seek a better life. Fate, however, had other plans for them.
Dr. Curt Connors is a scientist in the Marvel Universe who transforms into the vile Lizard, usually fighting Spider-Man.
The third Hobgoblin (Jason Macendale) became possessed by a demon after making a deal with N'Astirh. When Jason rid himself of the demon, the demon became Demogoblin. Ally of Carnage, enemy of Spider-Man and Venom.
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