Mages ultimately are more powerful but it's a slow burn. Might want to hold off on the arena. I would go for destruction + intelligence + something else (Depends if you're power leveling or not). Invisibility is a good spell.
Also, Oblivion gates can give you a sigil stone that increases your magika by 50 once you bind it to one of your clothing items, but it's random. Whenever you beat an Oblivion gate, save right before getting the stone. You can reload until you get the one with +50 magica. You can have 9 pieces of clothing equipped at once, if you don't cheat ;) . 9 X 50 = 450 extra points of magica.
Once you reach 100 destruction, you can basically create spells that break the game. If you have the wizard tower DLC, you can create spells right away, otherwise you have to beat the Mages guild quest line. The best spells involve 100% weakness to elements. 100% weakness to fire, ice, lightning, and magica (all for about 1 sec) + 10pts dmg fire, ice, lightning, and magica (for about 1 sec) (Might also want to add area of effect 10)= AMAZING SPELL. Even though it's low damage, the damage multiplies each time it hits (If you hit before the one sec is up). You can basically kill everything in the game in a few hits. If you bind this spell to a sword or dagger, you can also add poison weakness and damage. Dagger is probably more preferable, since it's all about the speed of the hits.
More fun spells:
Illusion: Basically anything that makes you totally invisible.
Illusion: Paralysis for about 3 sec.
Conjuration: Summon Storm atronach.
Conjuration: Summon Deadric armor.
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