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Commander Shepard is the main protagonist of the Mass Effect trilogy. Throughout the game, the player's decisions can affect Shepard's personality, consequently changing how both individuals and entire races view him/her and the human race. Key choices can even affect the outcomes of situations throughout the story.
Ambassador Donnel Udina is a human diplomat stationed on the Citadel. He thinks humans deserve more consideration in running galactic affairs.
EDI (Enhanced Defense Intelligence)is the on-board AI of the SSV Normandy SR2. It assists the helmsman in piloting the ship and relays information to the crew.
Father of Miranda Lawson and Oriana Lawson, as well as the former's nemesis and her reason for joining Cerberus.
A Vanguard in the Alliance Navy, Jacob Taylor is one of the few survivors of the Eden Prime massacre. He is the main protagonist of the iPhone game Mass Effect: Galaxy, and is a member of Shepard's squad in Mass Effect 2.
Known for his ruthless tactics and combat expertise, Leng is a Cerberus operative that is the Illusive Man's most trusted agent.
A top Lieutenant in Cerberus, Miranda oversaw the Lazarus Project, a project dedicated to bringing Commander Shepard back from the dead. She eventually joins Commander Shepard aboard the Normandy.
Oleg Petrovsky is a Cerberus officer in Mass Effect 3 who took control of Omega following Aria T'Loak's removal from the station.
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