I'd love to see Red Storm and Ubisoft tackle Tom Clancy's Jack Ryan character, without any movie tie-ins I mean. Either adapt one of his other Jack Ryan books (Cardinal of the Kremlin, Without Remorse, Debt of Honor, etc.) or a wholly new story. I'd personally see it done in a mixture of "Uncharted meets Alpha Protocol" with huge helpings of political intrigue, espionage, and whatnot.
Would just be nice to see Jack Ryan back.