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Spider-Man villain often associated with Spider-Slayers, along with his father, Spencer Smythe.
Owner of Tenpenny Tower.
A Doberman who works with Charles F. Muntz in the movie Up.
Diego Brando from Parallel World is one of major and final antagonist of JoJo part 7, who serves Funny Valentine to obtain all seven parts and kill Johnny Joestar.
The primary villain of Tomb Raider: Legend, Amanda was an old friend and archaeology partner to Lara Croft.
Victim of Jigsaw in the Saw franchise. Later she accompanies him in "helping" other people.
Lich from the World of Warcraft universe. He is located inside the dungeon Razorfen Downs.
Sometime Batman villain, sometime anti-hero. Rumored to be the son of The Joker.
Pinkerton Agent who serves as the main antagonist of Red Dead Redemption II.
Andrew Ryan is the founder of Rapture, the undersea Utopia that is the setting for BioShock. His name is a partial anagram of Ayn Rand, author of the novel Atlas Shrugged, which served as the main inspiration for Ryan's philosophies and aspects of BioShock's story.
Finished long after Dr. Gero's death by his self-aware supercomputer, Android 13 is specifically designed to destroy Goku. He can obtain a greater form once absorbing components from #14 and #15.
Finished long after Dr. Gero's death by his self-aware supercomputer, Android 14 is specifically designed to destroy Goku.
Finished long after Dr. Gero's death by his self-aware supercomputer, Android 15 is specifically designed to destroy Goku.
Android 19 was created by Dr. Gero to kill Goku. Unlike his previous creations, Android 19 is completely mechanical, and designed to absorb his opponent's life energy.
Andross is the arch-nemesis of Fox McCloud, star of the Star Fox games. He is part-monkey and uses telekinetic powers.
A nurse that serves as Lady X's assistant.
An antagonist in Red Dead Redemption II.
Angelo is the co-leader of Los Carnales, although it's obvious that Hector takes the bulk of the responsibilities.
Fantastic Four enemy who rules the Negative Zone in the Marvel Universe.
The heartless of Master Xehanort, and the main antagonist of the first Kingdom Hearts game.
Fascist dictator of Yara, and main antagonist of Far Cry 6.
Apocalypse is a mutant who is over 5000 years old. He believes strongly in "the survival of the fittest." He was portrayed by Oscar Issac in the 2016 film X-Men: Apocalypse.
Araj is a lich from the World of Warcraft.
Araskes, the Trickster, is a Baron of the Scorn.
Arcade is a supervillain/hitman in the Marvel Universe. He assassinates his victims by kidnapping them and setting them loose in a maze of deathtraps disguised as an amusement park called Murderworld.
Urthemiel was once one of the old gods of Tevinter before he was corrupted by the darkspawn and became the Archdemon of the Fifth Blight.
Leader of Team Aqua in Pokemon RSE.
A mythological Greek God. Son of Zeus, brother of Athena, Artemis and Apollo. He is the God of War and is unmarried. In mythology he has an affair with Aphrodite. He appears in many different games, most notably the God of War series.
Armaggon is a time-traveling mutant (or alien) shark from the Teenage Mutant Ninja Turtles series.
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