Alien vs Predator: The Last of His Clan is a side-scrolling action game developed by ASK Kodansha and published by Activision for the Game Boy. In Japan the game was published by ASK Kodansha.
Electronic Gaming Monthly's Mike Weigand gave the review score of 6 out of 10, writing, "As if the one for the Super NES wasn't enough, here comes the portable version. Unfortunately the game plays like it should be on a bigger format, like the 16-bit maybe. All the action is confined on the tiny litle GameBoy screen and there needs to be more responsive control".