In Armed and Delirious (also known as Granny, GrannyX, or Dementia) the player plays the Grandmother of a family and while she is asleep one day a cosmic rabbit comes down from space, steals her house, relocates it to an asteroid, and kidnaps her family. When Grandma wakes up the house is filled with strange creatures from outer space and other dimensions. The player then has to navigate grandma out of the house and across the galaxy to rescue her family.
The twist of the game is that Grandma suffers from massive senility and Alzheimer's Disease. Everything in the game is seen through the eyes of Grandma therefore none of it may be happening at all.