Born in Sydney, Australia, Claudia is best known for her roles as Aeryn Sun in Farscape from 1999-2003, and as Vala Mal Doran in Seasons 9-10 of Stargate SG-1, as well as appearing in the two Stargate SG-1 movies: The Ark of Truth and Continuum, and the Farscape movie The Peacekeeper Wars. She was nominated for a Saturn Award for Best Actress in 2001, 2002 and 2005 for her roles in Farscape, winning the award in 2005. Claudia has also been a supporting character in the movies Pitch Black and Queen of the Damned.
More recent work includes voice acting for the games Dragon Age: Origins and Dragon Age: Inquisition as Morrigan, Conan as A'Kanna, Crysis as Helena, Uncharted 2: Among Thieves as Chloe Frazer, and Mass Effect 2 as Admiral Xen. She was also an announcer for the 2009 Spike TV Video Game Awards.