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Osmund Saddler plays the role of the main antagonist in Resident Evil 4. He is the leader of the religious cult Los Illuminados.
Spencer is the President and Co-Founder of the Umbrella Corporation.
Ozzie Mandrill is an Australian land developer that plans to buy out the entire Caribbean and rid it off all pirates. Partner with LeChuck.
The President of the United States, leader of the Enclave and primary antagonist in Fallout 2.
Rendon Howe is Loghain's right hand man in Dragon Age: Origins. He is the cause for the Human Noble joining the Grey Wardens. He is a cruel and sadistic person.
Revolver Ocelot, aka Shalashaska, real name Adam, appears in the the Metal Gear Solid series with often unclear motives.
The main holy man of the Order of the Sword from the Devil May Cry Series.
Seth is a lonely widow living in Jackson County, Wyoming. He is well known as the creator of the Bigot Sandwich.
Mob boss and enemy of Spider-Man.
The third 'Son of Big Boss', created as part of the Les Enfants Terribles project along with Liquid and Solid Snake.
The number 1 guy at OCP.
Magruder is the main antagonist of GUN. He is in charge of the railroads being built through the Apache land, and in search of an ancient city of gold.
Vigo is the villain from Ghostbusters II. He makes an appearance in Ghostbusters: The Video Game, at the Firehouse hub levels.
Primary antagonist of Half-Life 2 and a general betrayer of humanity.
Warren is the main antagonist of Assassins Creed and the enemy of Desmond Miles. He is an employee of Abstergo industries.
Also known as Father Comstock or the prophet, he is responsible for the creation of Columbia. Comstock acts as the primary antagonist of BioShock Infinite.
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