So i am lvl 8 in my "super bad evil i kill everyone game" and im going to be running a 2nd game where im mr nice do all the missions i can game.
 
I never fully understood what the best perks/stats were, i have been pumping into guns/lockpick/survival and in perks i have been getting +10% exp, what should i be getting? what would benifit the end game?

I prefer high speech, but I'm also not shooting everyone I meet in the game... 

" I prefer high speech, but I'm also not shooting everyone I meet in the game...  "

Getting more exp is a waste of perk.  You've gotta think end game, cause you're going to be kicking yourself in the ass when you're not getting anymore exp and you could've picked up some extra encumberance strength.  Same with "Here and Now".  You'll reach a high level soon enough, good things come to those who wait.

I'm stunned on how many perks there are in this game. It's like a billion of 'em! But i did not get a perk on level 3. I thought we would get a perk every level?

every other level this time around...

The man-killer perk seemed like the best to start to me, and the +skill points per level and +skill points per book are my next two favs for starting 3.  The rest of the first few tiers of perks just aren't good enough, and it's better to make the early investment and get 100+ extra skill points over the game. 
 
Intelligence (for skill points / skills), Strength (for carry weight), and Agility (for AP) are my favorite stats, though I don't really favor heavy specialization as much in this game as I did in the original Fallouts.

In Fallout 3 I put a lot of my points into speech and picked speech based perks, but for New Vegas I thought I'd make a build with high science and weapon skills. Kind of regretting not making a build focused on speech again because it usually saves on tedious missions.

educated and comprehension are the best early game perks by far. pick em up at levels 4 and 6 respectively.
try to max agi and luck stats wise, but remember you can get implants.

best perk is black widow, obv.

Well, I don't want to spoil any of the perks, since I have the strategy guide and know 'em all, but there are some pretty good ones. One, specifically, let's you repair weapons with those that use the same ammo type, so it doesn't even have to be the same exact weapon. You need about 70 repair for that one, but it sounds pretty cool!

These are my perks. 

Traits

• Trigger Discipline
• Wild Wasteland

• Level 2 - Confirmed Bachelor
• Level 4 - Lady Killer
• Level 6 - Rapid Reload
• Level 8 - Comprehension
• Level 10 - Toughness (1)
• Level 12 - Toughness (2)
• Level 14 - Tag!
• Level 16 - Adamantium Skeleton
• Level 18 - Jury Rigging
• Level 20 - Explorer
• Level 22 - Intense Training (1 - Luck 6)
• Level 24 - Intense Training (2 - Luck 7)
• Level 26 - Intense Training (3 - Luck 8)
• Level 28 - Intense Training (4 - Luck 9)
• Level 30 - Intense Training (5 - Luck 10)