Roman is introduced early on as one of the main antagonists of the first Uncharted, Drakes Fortune. He is somewhat connected to Victor Sullivan through some bad circumstances involving money and has the player believe Victor dies when he shoots him at the chest.
Initially shown to be the main villain, he is eventually betrayed by his subordinate, Atoq Navarro, by being tricked into opening the cursed Golden Coffin and breathing in a mist that turns him insane. Navarro then shoots Roman through the head and reveals to have been manipulating him from the beginning, to which he then fills the place as the game's primary antagonist.
Like most characters featured, Roman is an in-game purchasable skin for the player to put over Drake.
With the release of the Uncharted: Drake's Fortune multiplayer pack for Uncharted 2: Among Thieves and its GOTY edition, Roman was added as a character skin on the side of the villains for the competitive multiplayer. He was also released as one of many DLC skins for Uncharted 3: Drake's Deception.