Ghost Manor is a side-scrolling platformer with a horror theme. The player, as Arthur, must venture into the haunted environs surrounding his hometown of Anoraff to reach the titular mansion and defeat Orb Gamut and his army of undead. He is gifted magical powers via a purple orb, which needs to be regularly refilled as it is Arthur's only means to fight the undead.
The game is an action adventure game in the same manner as the Dizzy games from Codemasters. While the player is expected to leap between platforms and fight monsters, they must also search around for items and solve inventory puzzles before they can continue. They can investigate suspicious areas by pressing up on the D-pad, which can result in an enemy trap or a useful item.