Indiana Jones and His Desktop Adventure is an overhead adventure game set in the 1930s in an indeterminate jungle environment. The player controls Dr. Jones in his encounters with Nazis, natives and local bandits. These enemies must be killed, or bypassed, in order to progress past a variety of puzzles.
Most of these puzzles consist of picking up an object to give to a person. Eventually the player will have to defeat a randomly generated boss and be awarded with a 'player IQ'.