I just recently went back and played through this game after finishing it once more than three years ago. It is still very good. I love the setting, the varied cases and cool characters.
It is sad to think that this game will probably never get a sequel.
Los Angeles was great, but i also think that Miami in the 1980s (Yes, very much a setting similar to Miami Vice which we all love.) would suit this style of game. Or perhaps San Fransisco in the 70s, or maybe Chicago in the 50s or 60s. Even the 90s are by know an era that would be fun to go back to, so I say New York in that time period as well. But there are so many cities, countries and possibilities!
What kind of city and era would you like a possible sequel to take place?