Lisa Hamiltion who is better known by her Luchador wrestler name La Mariposa made her initial debut in Dead or Alive Beach Volleyball. She was high-school friends with Tina Armstrong and made her first proper appearance in the main fighting roster in Dead or Alive 4. She was revealed to be a former scientist at DOATEC and was one of the key minds behind the Project Alpha project which spawned Alpha-152 the Kasumi clone. She watched over the test subjects for all of the projects she ran which included Kasumi and Hayate.
Her work was done out of DOATEC's Germany branch under direct orders from Victor Donovan. After an incident where Ryu Hayabusa attacked the DOATEC HQ in germany to rescue Kasumi Lisa fled with Hayate in a Helicopter but the escape was only minorly successful as the helicopter crashed separating Lisa and Hayate who eventually lost his memory and adopted the persona of Ein. Hitomi saved Lisa's life by pulling her from the wreckage.
Even after the Germany incident Lisa continued her research on the Alpha project. During the events of Dead or Alive 4 while the Mugen Tenshin clan attacked the DOATEC HQ she revealed to Hayate that she had been the one who had manipulated him. She had also previously revealed this to Helena Douglas and even threatened her life as a way to keep her silent. After the events of DOA 4 Lisa took up her professional wrestling again as her main career fighting alongside of her old time friend Tina Armstrong.
In the fifth tournament Lisa continues to work for Victor Donovan and his new organization MIST. During the final events of the fifth game it is unclear of the status of Lisa.