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Alex Shepherd is the protagonist of the video game Silent Hill: Homecoming.
The protagonist in Red Faction 2.
Dracula's not-quite-so-loving son from the Castlevania franchise. He is a vampire who fights against his father on the side of good.
After witnessing the cold-blooded murder of his parents, young Bruce Wayne swore to combat the evil that took their lives. Using his family's fortune, he travelled the world, training to physical and mental perfection. Once his training was complete, he returned to Gotham City as the Dark Knight, Batman.
A drug addict dying of cancer searching for his son, Campbell becomes an unwilling pawn of Jigsaw.
Carrie is a girl with gifted magic powers. She is a descendant of the sorceress Sypha Belnades.
Chuck Greene is a former national motocross champion and the main character of Dead Rising 2 and Dead Rising 2: Case Zero. He is the father of Katey Greene and must constantly acquire Zombrex for her.
Cole is the protagonist of inFamous. He gains electricity-based superpowers in the explosion that cripples his hometown, and must choose whether to use them to defend or destroy Empire City. He has a tendency to slowly think out his choices and their possible consequences.
Commander Shepard is the main protagonist of the Mass Effect trilogy. Throughout the game, the player's decisions can affect Shepard's personality, consequently changing how both individuals and entire races view him/her and the human race. Key choices can even affect the outcomes of situations throughout the story.
Crono is the silent protagonist of Chrono Trigger. With his big hair, big sword and lots of courage, he and his friends are ready to save the world from Lavos.
The Demi-Fiend is the protagonist of Shin Megami Tensei: Nocturne. Half human, half demon, his powers are the deciding factor in the shape of the new creation to come.
Dr. Wagner is Marie Bonds' surgeon in Police Quest 3.
Frank West is a freelance photographer and the protagonist of Dead Rising.
He's covered wars, ya know.
An enigmatic character of disturbing power, the inhuman G-Man represents an unknown, trans-dimensional organization, and is a major influence on the events in the Half-Life universe.
Gordon Freeman is the popular and critically acclaimed main character in Valve Software's Half-Life series, and one of most well-recognized examples of the silent-protagonist.
The protagonist in the original Silent Hill, Harry Mason searches for his adopted daughter Cheryl in the town of Silent HIll. He makes an appearance, albeit short, in Silent Hill 3.
Heather Mason is the protagonist from Silent Hill 3, and the reincarnation of Alessa Gillespie. She is given to Harry Mason at the end of the original Silent Hill.
Henry Townshend is the protagonist of Silent Hill 4: The Room. He finds himself trapped in his apartment, and travels to Silent Hill through a mysterious hole in his bathroom wall.
James Sunderland is the main character in the Konami video game Silent Hill 2. He comes to town searching for his wife.
Kuros is the main character in the Wizards & Warriors trilogy on the NES.
The Lone Wanderer is the protagonist of Fallout 3. It is this person's mission in the game to find his or her father, who mysteriously left Vault 101.
Wife of Detective David Tapp's deceased partner. She is seen in SAW the video game.
The player-controlled main character in Shin Megami Tensei: Strange Journey. He is at the forefront of the exploration of the mysterious Schwarzwelt.
The main character from Blade Runner, the PC adventure game from 1997. Ray is a Blade Runner on the hunt after replicants that have escaped to earth and he is voiced by Mark Benninghofen.
Samus Aran is the protagonist of the Metroid series. As a bounty hunter, she uses her armored power suit to hunt space pirates and other dangerous forces. She frequently crosses paths with dangerous creatures called Metroids in her adventures.
Soma Cruz is the protagonist of Castlevania: Aria of Sorrow and the sequel Castlevania: Dawn of Sorrow. He is capable of absorbing the souls of demons, thereby acquiring their powers.
The main character of the X-Change series.
An Assassin from the SSF, who had the ability to turn Invisible. She later joined the Red Faction to fight Sopot's tyranny.
The main character of the Saints Row series and, as of Saints Row 2, the leader of the 3rd Street Saints.
An Artificial Intelligence that plays a role in Mass Effect 3.
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