Nakajima Satoru Kanshuu F-1 Grand Prix is the first game in the Nakajoma Satoru F-1 series to be released on the Sega Mega Drive, and the first 16-bit game in the series. It is endorsed by professional racer Satoru Nakajima and was followed in 1992 by Nakajima Satoru Kanshuu F-1 Hero MD, best known overseas as Ferrari Grand Prix Challenge.
The game uses a top-down perspective of the course with on-screen warning signs for upcoming corners in the track. There's also a mini-map the player can use to prepare for hairpin turns and other tricky course features. The player can customize their F1 vehicle to some extent before the race begins, using a selection of different parts for each component of the vehicle.