Your top 5 ? 

Don't really have a top five (not that I don't have five faves I just suck at lists) but Uncharted 2 is hands down my favorite PS3 exclusive and favorite game of last year and a long with Mass Effect 2 pretty much tied up in my mind as best game this gen.

Ratchet and Clank (tools of destruction and crack in time) 
Fat Princess 
Lead and Gold 
Infamous

Demon's Souls
Uncharted 1 + 2
inFAMOUS
Metal Gear Solid 4

Little Big Planet
Pixel Junk Monsters
Uncharted 2 
Echochrome. (even though I suck at it and it hurts my brain)

in no order:
 
inFamous
Little Big Planet
Uncharted 2
Modnation Racers
Rock Band 2 (you didn't say exclusive but I'd probably swap this for metal gear solid 4 or god of war 3 if that were the case)

1. Valkyria Chronicles (four stars)
2. Demon's Souls (four stars)
3. inFamous (four stars)
4. Killzone 2 (three stars)
5. God of War III (two stars)

• Uncharted 2
• LBP
• PixelJunk Eden
• Metal Gear Solid 4
• InFamous

• LPB
• Uncharted 2
• Fat Princess
• MLB 10: The Show
• Killzone 2
  

Metal Gear Solid 4, Killzone 2 (Only for the multiplayer), and Demon's Souls.

Are we talking PS3 exclusives here? If so, then:  

1. Uncharted 2
2. Metal Gear Solid 4
3. Ratchet and Clank: A Crack in Time
4. Valkyria Chronicles
5. Uncharted: Drake's Fortune

• Pixeljunk Shooter
• God of War III
• Killzone 2

Uncharted 2 
inFAMOUS 
Resistance 2 
EDIT: Demon's Souls...completely forgot O_O
Burn Zombie Burn

• Uncharted 2

• Infamous

• Joe Danger

• Motorstorm: Pacific Rift
• Little Big Planet

1. Metal Gear Solid 4
2. Uncharted 2
3. Infamous
4. Heavy Rain
5. Little Big Planet

God of War 3, Infamous, Uncharted 2, Pixel Junk Eden, and Wipeout HD.

1. Uncharted 2 - A masterpiece. Don't really need any other description.
2. Demon's Souls - My first console action RPG. A great but somewhat poorly designed storyline. Cool level designs. Tons of customization. "New game plus" and unique items gives many incentives for replays. 
3. Killzone 2 - Its graphics pushed me to buy a ps3. A pretty satisfying campaign. Great multilayer. Feels like the "man" of FPS's.  
4. God of War 3- Representing its genre's best. The first level alone is more eye-popping than the previous two installments. Like many others, I was put in constant awe by the spectacular artworks of violence. 
5. Heavy Rain - After my playthrough I felt satisfied. Expect it to be a mature game and it will reward the patient player with a experience that is unique and different. 
 
Notable mention: Red dead redemption - Great environments. Great campaign overall. Somewhat lacking multilayer. 

valkyria chronicles, metal gears solid 4, disgaea 3 absence of justice and yakuza 3

1. Demon's Souls 
2. Demon's Souls 
3. Demon's Souls  
4. Demon's Souls 
5. Demon's Souls

1. Demon's Souls
2. Valkyria Chronicles
3. Uncharted 2
4. Pixeljunk Monsters
5. MGS4
 
Pixeljunk Eden gets an honorable mention if for nothing else than the soundtrack and trippy visuals.

No particular order for me 
 God of war 3 
Uncharted 2 
Socom confrontation 
Pixel junk shooter 
MGS4

1. Uncharted 2
2. LittleBigPlanet
3. Heavy Rain
4. God of War III
5. Uncharted: Drake's Fortune
   

1. MAG 
2. Batman: Arkham Asylum 
3. Red Dead Redemption 
4. Uncharted: Drake's Fortune 
5. Toy Story 3

If we're talking a strict choice of my top 5 exclusive titles in no particular order

-Uncharted
-Uncharted 2
-inFamous
-ModNation Racers
-Heavy Rain 
 
and here's my top 5 PSN titles (not exclusive though)
 
-Trine
-Braid
-Joe Danger
-Fat Princess
-Shank

My list would appear to diverge a bit from the others: 

1. Battlefield: Bad Company 2
2. Fight Night: Round 4
3. The Godfather 2
4. Heavy Rain
5. An empty slot: To symbolize the utter lack of playable games for the Playstation in its third generation.

In no real particular order: 
* Demon's Souls (for bringing back the old school)
* Flower  (f-ck yeah!) 
* Pixeljunk Eden (so soothing) 
* Uncharted 2 (for excellent narrative devices) 
* Heavy Rain

Borderlands
Fallout 3
Fat Princess
Penny Arcade RSPoD2
Dj Hero

" Don't really have a top five (not that I don't have five faves I just suck at lists) but Uncharted 2 is hands down my favorite PS3 exclusive and favorite game of last year and a long with Mass Effect 2 pretty much tied up in my mind as best game this gen. "

MGS4 
GOW3 
Uncharted 2 
Ratchet And Clank: A Crack in Time 
Little Big Planet 
 
In that order

1. Ratchet and Clank Future: A Crack in Time
2. Uncharted 2
3. God of War 3
4. Heavy Rain
5.  Infamous
Joke answer is FF 13 because the 360 port is just awful and should be wiped off this plane of existence.

Uncharted 2 
Metal Gear Solid 4 
Heavy Rain 
Uncharted 
Condemned 2: Bloodshot

• 3D Dot Game Heroes
• Yakuza 3
• Uncharted 2
• Demon's Souls
• Zen Pinball

Uhh do they have to be exclusives?  
 

1. Infamous 
2. Uncharted 2  
3.  Heavy Rain 
4.  God of War 3 
5. Ratchet and Clank Future Tools of Destruction

Personal PS3 Collection

	1. Valkyria Chronicles This is the game I wanted most for the PS3. The unique style, combined with the unique gameplay mechanics, made the package incredibly appealing. In retrospect, I probably should have bought this one new in order to support the studio that made it (the game didn't sell well) but either way I'm happy I've got it. This will be the first game I actually play.
	2. Metal Gear Solid 4: Guns of the Patriots This is the first game that I really wanted for the PS3, and for a long time it was the only one. I've always been interested in the plight of Solid Snake, and will get to this as soon as I play 2 and 3.
	3. Heavy Rain I am in the process of playing Indigo Prophecy at this moment. As soon as I saw this game at PAX 09 last year, I knew I wanted this game. I was initially skeptical when the game was first announced, because all the focus was on the graphical prowess, making the term "uncanny valley" a term frequently connected with the current gen. Over time, the game lost the creepy realism, but more of the game play was revealed, and thats when I became more interested.
	4. Uncharted: Drake's Fortune I'm pretty much buying this because it comes before Uncharted 2, and I don't play narrative-based series out of order.
	5. Uncharted 2: Among Thieves Theres really not much that needs to be said here, since U2 is easily the highest rated game on the console. I didn't enjoy what I played of the demo at PAX (too much Assassins Creed climbing for my taste) but with all the critical praise the game has received, I'm willing to give it a second chance.
	6. inFamous This was almost a throw-in. When the game was initially announced I was pretty interested in the idea of an electric super anti-hero. Almost like the Static Shock game that doesn't exist yet, but should. But when I saw videos of the game, I realized that it was essentially another third person shooter. In fact, nearly all of these games are third person shooters. And this fact was one that turned me off of the PS3 library for a long while (in conjunction with a number of other things).

MGS4
Uncharted 2
Uncharted
Little Big Planet
inFamous

LBP
WipEout HD (Fury) 
MGS 4
Yakuza 3
 Demon's Souls

I'm going to get killed but:
 
Alpha Protocol
Killzone 2
Mafia 2
Heavenly Sword (Gorgeous cinematics. Can't wait for Enslaved)
Fallout 3 (even thought the stupid DLC makes my PS3 freeze up still. Thanks for the no-patch Bethesda)
 
Oh, and Uncharted 2 is pretty cool I guess ;)

Heavy Rain
Little Big Planet
Uncharted Series
Metal Gear Solid 4
God of War III

Katamari Forever
Valkyria Chronicles
SingStar
White Knight Chronicles
PixelJunk Shooter

In no particular order~
Demon's souls~
Disgaea 3~
Infamous~
Yakuza 3~
Blazblue: CT/CS~ (Does it count~?)

1. Demons souls
2.mgs4
3. valkyria chronicles
4.yakuza 3
5.kz2

- Metal Gear Solid 4

- MAG

- Uncharted 2

- Final Fantasy XIII

- Yakuza 3

• Little Big Planet
• Uncharted 1 & 2
• inFAMOUS
• flower
• Metal Gear Solid 4
  

1. InFamous  
2. Resistance 2 
3.  MLB: The Show (pick a year, they're all a blast) 
4.  Ratchet and Clank Future 
5. Disgaea 3
 
Honorable mentions go out to Shatter, Wipeout HD, and the PS originals program.  Love me some old PS1 RPG's without having to worry about disc maintenance.

1. uncharted 2
2. little big planet
3. uncharted 1
4. Arkham asylum
5. Killzone 3  (edit: on my non future list is Killzone 2)
 
Not sure if the order is like that, but those five games come to mind, and Uncharted 2, is a certain number 1.

Top 5 In order: 
1) MGS4  
2) inFAMOUS
3) Demon's Souls 
4) Uncharted 2 
5) Killzone 2 

Demon Souls & Metal Gear Solid 4 :D

1. Uncharted 2 
2. MGS4 
3. God Of War 3 
4. Killzone 2 
5. InFamous

inFAMOUS 
Uncharted 2 
Heavy Rain 
MGS4 
LittleBigPlanet 
 
Woah, I was lucky to name 5 games there.

1. Uncharted 2  
2. Killzone 2 
3. MGS4 
4. InFamous  
5. Heavy Rain