I'd hold on to the cash for now, play some more of my back-log, and then re-fill the backlog with last year's $20 offerings from Target or Walmart. For example, Orange Box, Dead Space, and Burnout Paradise, I found for $20 each. You can't beat that.
I loved Uncharted 2, but in my opinion, Game of the Year should bring something new to the table. Uncharted 2 does some really nice things, but it's really just a new story, using the same formula as Uncharted 1. The gameplay differences are minor. Granted, the production values are retarded good. The co-op and multiplayer help flesh it out a bit, but I still think that, so far, having not played much of the new stuff:
Batman: Arkham Asylum has left the biggest mark on me this year. It's a new game franchise, done in a way we haven't seen before, from a developer in which we're not familiar. It captures Arkham very well by making great use of the source material.
It's too soon for me to be rating my 2009 games of the year, because I haven't had a chance to play everything just yet. Also, I think it's best to wait a while before judging a game's long term quality. Often times games burn hot, but are forgettable in the long run. So, I'm just getting around to last year's list:
2008 Game of the Year: http://whatwouldjesusview.com/2008-game-year.html