@rorie: I'm mining on an AMD card directly to a pool so it may be different (but i dont see why it should). Lowering core voltage will lower power consumption and temperature but will cause the GPU more likely to crash. I didn't notice this affecting my hash power. Changing core clock or memory clock (depending on the bottleneck of the GPU) affects the hash power. It's a matter of balancing how high you can get the clocks and how low the core voltage is while keeping everything stable. This is why people flash the GPU's bios but that seems scary so i just use afterburner.
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