Square-Enix showed a video at e3 announcing an iPhone version of Secret of Mana to be released in 2010. They only showed the intro, no gameplay. (And no info on multiplayer or whether they're adding pathfinding.)
 
I'm guessing it's going to be a port of the Japan-only mobile phone version, rather than the proper remake I've been dreaming of. Sigh.

Here's the teaser on YouTube.

This is great news :)

Gameplay video from Japanese site AppBank: