Please feel free to post moments from throughout the years at Giantbomb where Jeff dropped a HIP HOP refernce. To kick us off here's two I remember.
During the Mass Effect Legendary edition quick look at 45:50 into the quick look Jeff says "walk around the metal detectors". There by referencing the 2004 club banger, Lean Back by Fat Joe. Specifically the part in the song where Remy Ma raps "we don't pay admission, the bouncers don't check us and we walk around the metal detecors".
Going back a litltle now to Destiny's DLC The Taken King Quick Look. At 55:40 into the quick look Jeff drops the line "their the osiris of this shit", referencing the classic Wu-Tang posse cut Triumph. The reference in question is Old Dirty Bastard's monologue at the start of the song.
Lets keep digging in the crates!