If my opponent uses a 3rd level X-factor, I typically use it on my second to last guy instead of my last one. I'm doing a lot better vs Sentinels now. One trick I use is to rush in and block. It's tough to get in when they have a good vertical assist, though.
I really am looking forward to this game. I haven't bought a game in nearly a year (I am a Gamefly aficionado), and so I only drop 60$ on stuff I know will last months in my 360. This game just gives me that feeling. MvC3 will probably be one of my only game purchases of 2011 and I'm not worried about losing out on my investment. If they pull off DLC right, it could stay in my XBox for a year+.
I imagine this game would be perfect as a rent-before-buy game, too (and you could end up saving ~10$ on a used copy).
To me, it's more like if you didn't feel anything when doing some sort of in-game action, it's because you weren't supposed to. The director in a movie can make a death tragic using his various moviemaking tools, and the same goes for games.
For example, I was really sad to have to take out Wrex. Once you realize you have to kill that guy (sans good enough charisma), it kind of puts more weight on your dialog choices (did anyone else fully level up their charm/intimidate skill after failing the Wrex scene?).
Morrowind really made me think about who I let live and die, too.
That 'On to the Next One' video, I think, was specifically made to contain a bunch of unrelated shit so that conspiracists would make something out of nothing. The 'Monster' video was atrocious, no need to look for any messages in a music video that sucks so bad =p