Samara is a loner, not a leader. You lose your tech specialist if you pick a bad squad leader.
Losing Garus or Tali negatively effects ME3. I get the whole "deal with your choices" thing, but I can't imagine ME3 without Tali, especially because of some of the major choices she's involved with.
I work in a restaurant and decided to order 2.3 pounds of seaweed salad from our food supplier. Eating almost 2 pounds of seaweed salad in one sitting is a good way to ruin seaweed salad forever, so I can relate to that sweet corn story.
Pfhor's comments