At the first resistance camp and I'm struggling to maintain 60fps. With 8x anti aliasing and everything maxed at 1440p I get around 45 fps, GTX 1070 and 4790k.
I knock everything down to medium preset, and it's still not staying at 60, somewhere between 50-60. Not bad, but if I tweak I can get slightly better quality and the same performance.
Sweet spot so far has been 2x AA, with medium shadows. Seems pretty good. Hope they iron it out. But it seems the game isn't made to run over 1080p at 60.
Like @crommi said, AA is very expensive in this game. I recommend turning it off and injecting an external solution that costs less. That way you shouldn't have to knock things down to medium. Definitely keep shadows on high.