I'll second Comedy Bang Bang, My Brother My Brother and Me, and Conan O'Brien needs a friend. If you like those there are more podcasts by the same people or on their networks.
The host of CBB has another show with Parks and Recreation's Adam Scott where they discuss the music of U2 and REM, but mostly just goof around. In addition to MBMBAM's hosts many other shows, they are a part of a network with similar shows of funny people chatting like Jordan Jessie Go and Stop Podcasting Yourself.
Doug Loves Movies is similar, he does live shows with comedians where they goof around and play movie games. Not sure how that's doing right now with the virus, but there's an extensive back catalog.