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Andrew Ryan is the founder of Rapture, the undersea Utopia that is the setting for BioShock. His name is a partial anagram of Ayn Rand, author of the novel Atlas Shrugged, which served as the main inspiration for Ryan's philosophies and aspects of BioShock's story.
Armor is a member of the X-Men who is capable of projecting a psionic armor around herself.
A blunt, no nonsense marine, Gunnery Chief Ashley Williams is one of the first squadmates who joins the crew in Mass Effect. She remains with Commander Shepard potentially throughout the game, and if pursued, can be a male Commander Shepard's love interest.
The cunning, intelligent, and ruthless arch-enemy of Andrew Ryan, and the leader of the opposition in the power struggle which led to Rapture's collapse.
One half of the Frontier Brain for Castle Valet in Pokemon HeartGold/SoulSilver/Platinum whom later became one of Unova's Elite Four in Pokemon Black/White.
Cassandra Nova is the evil twin sister of Charles Xavier.
Commander Shepard is the main protagonist of the Mass Effect trilogy. Throughout the game, the player's decisions can affect Shepard's personality, consequently changing how both individuals and entire races view him/her and the human race. Key choices can even affect the outcomes of situations throughout the story.
A Cheyenne member of the New Mutants, X-Men, and Valkyries who has gone under different code names but is best known under her real one.
An African psychic who raised Kukri. She joins Heidern and Isla on Team Rival in The King of Fighters XV.
Emma Steed is a very powerful telepath and a member of the Hellfire Club
Garrus Vakarian is a Turian Agent and member of C-Sec. He is a possible squad member in all three Mass Effect games.
A Krogan who joins Commander Shepard's team in Mass Effect 2. He is younger than Wrex, but just as aggressive if not more. In his debut trailer he was seen charging the enemy similar to the Krogan warlords in the original game.
A powerful biotic, Subject Zero is one of the new crew members for Mass Effect 2. Shepard first encounters her on the prison ship Purgatory.
Jack is the silent player character in BioShock. After surviving a plane crash in the middle of the Atlantic Ocean, he stumbles upon the underwater metropolis of Rapture.
A Vanguard in the Alliance Navy, Jacob Taylor is one of the few survivors of the Eden Prime massacre. He is the main protagonist of the iPhone game Mass Effect: Galaxy, and is a member of Shepard's squad in Mass Effect 2.
A human team member who accompanies Commander Shepard from the beginning of Mass Effect. Kaiden is skilled in both Biotics and Tech, but struggles to keep control, due to the physical side-effects of his implanting.
Kamille Bidan, considered the strongest Newtype in the Gundam franchise, is the main character of Zeta Gundam and pilot of the titular mobile suit. A teenager full of rage, Kamille fights against the elite Earth Federation forces known as the Titans.
Kasumi is a master thief hired by Cerberus to aid Commander Shepard on his mission to stop the Collectors.
Kid X is the son of Charles Xavier and Mystique.
Regan Wyngarde is one of three daughters of the mutant villain Mastermind.
Legion is the son of Professor Xavier. He is an ultra-powerful mutant with thousands of different personalities, each of which has its own powers.
Manchester Black is the leader of The Elite, an English anti-hero team in DC comics.
Miranda is one of four sacred sisters of Mille Seseau. She also ends up helping Dart and the rest of the team.
A top Lieutenant in Cerberus, Miranda oversaw the Lazarus Project, a project dedicated to bringing Commander Shepard back from the dead. She eventually joins Commander Shepard aboard the Normandy.
Mordin Solus is a recruitable Salarian scientist in Mass Effect 2. He is a fast-talking scientist that speaks in very short sentences; he is also noted as a fine singer.
From the Mass Effect franchise, Morinth is daughter of Samara and one of the three known Ardat-Yakshi, a genetic branch of Asari with a mating defect which results in the death of their partner. Morinth chooses to use this to dominate and destroy the minds of unsuspecting victims.
The main protagonist of EarthBound. Ness is a young boy who uses his psychic abilities to save the world from the evil Giygas.
No-Girl is a telepathic mutant who exists as a disembodied brain.
A young girl from Twoson and gifted psychic, Paula focuses on offensive PSI abilities and is the second playable character to join the party in EarthBound.
The crown prince of the far-away land of Dalaam. He joins Ness as the fourth and final playable character in EarthBound.
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