Rod Humble began his career working at publisher and development studio GameTek, where he did a variety of jobs from writing manuals to designing games. He later left GameTek and was hired by Virgin Interactive where he designed the game Subspace alongside colleague Jeff Petersen. After his stint at Virgin, he began work at Sony Online Entertainment where he designed and produced Infantry, and worked on EverQuest. On October 7 2008, Humble became the Executive Vice President of the EA Play label and the head of The Sims franchise at EA where he worked on both The Sims 2 and The Sims 3.
Humble led the Play label at EA until 23 December 2010, when it was announced he was leaving EA to become the CEO of Linden Lab, the developers of Second Life, in January 2011. Outside of his professional development, Humble has worked on a number of his own experimental art games; The Marriage, Stars over Half Moon Bay, and Last Thoughts of the Aurochs.
- Humble makes a cameo in The Sims 2: Free Time where he appears as an NPC that will deliver players a computer.