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A traitor and enemy to the vast majority of Resident Evil's protagonists, Albert Wesker has rapidly achieved super-villain status within the series canon.
Ashley Graham is daughter of the President of the United States. Leon S. Kennedy's mission during the events of Resident Evil 4, is to rescue Ashley.
Ingrid Hunnigan is Leon S. Kennedy's support and radio contact throughout the Resident Evil franchise after he becomes a US Government agent.
Leon Kennedy was an R.P.D. officer who survived the Raccoon City outbreak. He is now a skilled government agent tasked with the extermination of biological weapons created by the Umbrella Corporation.
Supporting character in Resident Evil 4, Luis is an ex-police officer from a remote village in Spain, who now seems to hold some relation to the Los Illuminados cult.
Ramon Salazar is one of the main antagonists in the game Resident Evil 4. He runs the castle mid-game and has a small stature.
The shady, unnamed merchant in Resident Evil 4. He supplies the character with weapons, weapon upgrades, and healing items along his journey. Sadly, to the detriment of the franchise at large, the Merchant has never appeared since.
U3 is a creature sent by Osmund Saddler in an attempt to kill Leon S. Kennedy. U3 is also referred to as "It".
The Verdugo (which is spanish for Executioner) is a sub-boss in the game, Resident Evil 4. They also serve as Ramon Salazar's body guards. He is one of the few bosses in the game that Leon doesn't have to defeat.
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