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EDI (Enhanced Defense Intelligence)is the on-board AI of the SSV Normandy SR2. It assists the helmsman in piloting the ship and relays information to the crew.
Medusa is often portrayed in games as a creature that is a cross between a woman and a snake. The lower body is often a snake tail, and the hair is usually a mass of snakes. Other than this, the head and torso are that of a woman.
Killer Croc is a nemesis of Batman. Once a man, he inherited a disease causing him to gradually lose all semblance of humanity, gaining reptilian traits in their stead.
The Illusive Man is the leader of the Cerberus group mentioned in Mass Effect. His goal with the Cerberus project is to make humans the most powerful race in the galaxy.
A human team member who accompanies Commander Shepard from the beginning of Mass Effect. Kaiden is skilled in both Biotics and Tech, but struggles to keep control, due to the physical side-effects of his implanting.
Black Adam's wife, who tries to change him for the better.
Shazam (Jebediah of Canaan) is the ancient wizard who empowered Billy Batson and other assorted beings with powers by invoking his name.
Commander Shepard is the main protagonist of the Mass Effect trilogy. Throughout the game, the player's decisions can affect Shepard's personality, consequently changing how both individuals and entire races view him/her and the human race. Key choices can even affect the outcomes of situations throughout the story.
In the Mass Effect series, Harbinger is the first Reaper ever made who manipulates the Collectors against Commander Shepard.
James Gordon is the Police Commissioner of Gotham City. Despite Batman's dubious methods of law enforcement, Gordon co-operates and assists him, allowing his crusade on crime to proceed unabated. He is also the father of Barbara Gordon AKA Batgirl (and Oracle)
Admiral Daro'Xen vas Moreh is a member of the quarian Admiralty Board. She is known for her keen scientific interest in the geth.
Poseidon is the son of Cronos and Rhea. When he was born Cronos swallowed him whole and he survived and grew inside Cronos' belly due to his immortality. He grew inside the belly of Cronos with his other siblings until Zeus freed him and his siblings. They then waged war against the Titans.
Revered necromancer and anti-villain of Dark Messiah of Might & Magic.
Conrad Verner is a huge fan of Commander Shepard. He can be found in the Upper Markets of the Wards in Mass Effect 1 and returns in Mass Effect 2 wearing replica N7 armor and can be found in a bar on Illium.
Kratos and Lysandra's daughter.
The ship captain from the God of War games, a running gag in the series. Kratos goes out of his way to take what he has and kill him, repeatedly.
Gorilla Grodd is an intelligent gorilla from DC Comics.
Admiral Shala'Raan vas Tonbay is a member of the quarian Admiralty Board. She is an old friend of Tali'Zorah's father, having known the Zorah family for over 25 years.
The Barbarian King was the the leader of the Barbarian army. He was killed by Kratos after Kratos gained the Blades of Chaos. His army caused Kratos to serve Ares leading to the events of the series.
Raiden is the Thunder God, protector of Earthrealm and a regular kombatant in the Mortal Kombat franchise.
Sareth is a wizard's apprentice, and the protagonist of Dark Messiah of Might & Magic.
Thane is the most feared assassin in the Mass Effect galaxy.
One of Superman's greatest enemies.
Killer Frost traditionally appeared as an enemy to Firestorm in the old comics.
Dr. Chakwas is the Chief medical officer of the Normandy in Mass Effect 1, 2, and 3. She is very polite and exhibits a mother-like attitude towards the crew.
A primordial deity of Greek mythology considered the personification of Earth. She and Uranas, the Sky, brought forth the greater host of heavenly beings.
Often seen as the main protagonist of the Mortal Kombat series, Liu Kang is a Shaolin monk who becomes the Champion of Earthrealm. Although he has died in multiple timelines, he later forges his own timeline as a Fire God.
A Greek god, brother to Zeus and Poseidon. He is either the fearsome yet just ruler of the Greek underworld, or a malicious Devil-esque figure, depending on the version.
Admiral Steven Hackett is the commanding officer of the fifth fleet and an admiral in the Alliance Navy. During the events of Mass Effect, he gives Commander Shepard optional assignments related to the Systems Alliance. He is stationed at Arcturus Station.
Bane is a character from the DC Universe best known for breaking Batman's back. He was played by the late Robert "Jeep" Swenson in the film Batman & Robin and played by Tom Hardy in the film "The Dark Knight Rises".
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