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Seymour Skinner is the principal of Springfield Elementary School.
Jackson is one of the two playable characters in Call of Duty 4. He is a member of the Force Recon squad searching for Al-Asad at the beginning of the game.
Sgt. Roebuck is your squad leader in Call Of Duty: World At War in the American campaign. He is voiced by Keifer Sutherland.
Shark is a Pit Bull that Billie Eilish adopted and took care of.
The infant son of the Sole Survivor who grows up to be Father, the leader of the Institute in Fallout 4.
Shaun Alexander is an NFL running back who has played for the Seattle Seahawks and Arizona Cardinals. He appeared as cover athlete on Madden 07.
A member of the Order of Assassins. He helps Desmond recover his ancestor, Ezio's memories.
Shaun Mars is son of Ethan and Grace Mars, and younger brother to Jason in Heavy Rain. He is kidnapped by the Origami Killer, who intends to make the boy his latest victim if Ethan cannot save him.
American professional snowboarder, skier, mountain biker, and motocross rider. Nicknamed "Napalm" and "Palm Daddy", he is known as one of the forefathers of extreme sports.
Springfield's only female bully and Daughter of Superintendent Chalmers.
Shaundi is one of the lieutenants in the Third Street Saints.
Shay Patrick Cormac is the protagonist in Assassin's Creed: Rogue.
She-Hulk is a super-heroine in the Marvel universe. She gained her powers from a blood transfusion with her cousin, Bruce Banner, aka the Hulk.
Sheana is a playable character in Tough Guy.
Sheldon Brown is a professional football-ist who played 8 seasons for the Philadelphia Eagles and is going into his second season with the Cleveland Browns. Brown is known for his hard hits.
One of the characters from Rockstar's Bully.
Shelton Benjamin is a professional wrestler currently wrestling with WWE.
Sarah Breaker is a young and intelligent woman who works as the chief law enforcer in Bright Falls.
Earl Whitehorse the sheriff of Hope County, and enlists the help of the Junior Deputy to bring the Seeds to justice.
Shimmer was Ellie's personal horse that she used for patrols in Jackson County.
A hero in DC online
The youngest Ozawa brother, and leader of the school gang "The Rivals". He clashes with Jiro over his protectiveness and their mutual attraction to Michelle Walter.
Streets of Rage 2's penultimate boss who returned as a boss and hidden character in the sequel. He is named after Shiva, the Hindu god of destruction. He can be played as a secret character in Streets of Rage 3.
Shogo Akuji is the young leader of the the Ronin gang. His father is Kazuo Akuji.
Shorty is one of the residents of Big Town who is taken to the Germantown Police HQ. Surprisingly, he actually is vertically challenged.
Friend of Ryuhi's. American teenage psychic luchador.
Shrapnel is the co-owner of Flak 'N Shrapnel's weapons and ammunition store in Rivet City.
Sidney Pen, also known under the alias of 'The Fat Man', is a minor character in the Empire Bay underworld of Mafia II. He appeared relatively frequently in pre-release trailers.
SIE is a mercenary born in East Germany, and a potential "love interest" in the spy RPG Alpha Protocol. Her real name remains unknown.
Daughter of Robert Knox and professional race car driver, who appears as a target in Hitman 2.
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