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A recurring Hulk villian. A former KGB agent who deliberately exposed himself to the same radiation that transformed Bruce Banner.
Adder is a Black Hole CO who has no particular strengths or weaknesses. However, his CO power fills quickly and gives him a wider range of movement.
As the leader of the Nazis, Adolf Hitler has appeared as an antagonist in several video games. Commonly considered the worst person ever, if you get the chance to kill him, you probably should.
The main antagonist of A Link to the Past, Agahnim is an evil wizard and the alter-ego of Ganon.
From the line of the Black Númenóreans, he is considered one of Sauron's most treacherous allies. He has a mysterious role in the War in the North.
A Mars Adept from Prox, who travels with Karst in a quest to release Alchemy back into the world.
Agony is a child symbiote of Venom, enemy of Spider-Man.
Ahriman is the dark force of destruction and corruption in Zoroastrian mythology. He is the opposing force to Ahura Mazda, the god of light.
A spider god in Mochica culture. He became the second Dark Spider-Man in Marvel Comics.
The "shape shifting demon" from the Samurai Jack cartoons on Cartoon Network. He was almost defeated by Samurai Jack, but he cast a spell that sent Jack into the future, where he was much more powerful and had a lot more allies.
Akuma (known as Gouki in Japan) is a major character in the Street Fighter series. His purpose is to defeat the strongest of foes, even if his victory can be murderous.
Altair's master and the leader of the Assassins. "Al-Mualim" literally means "The Teacher" in Arabic.
A traitor and enemy to the vast majority of Resident Evil's protagonists, Albert Wesker has rapidly achieved super-villain status within the series canon.
A character in Batman: Arkham Origins.
The elderly telekinetic villain of inFamous and the leader of the Dust Men.
Aldrich Killian is a scientist who was involved with the development of the Extremis virus.
Bond Villain, formerly part of MI6 where his codename was 006.
Has appeared in the N64 version of Goldeneye as well as the remake on DS & Wii
A mostly unseen character, Alexander plays a pivotal role regarding the founding of Umbrella, and is the father of twins Alfred and Alexia Ashford.
One of the main characters in Resident Evil Code: Veronica. He is a descendant of one of the founders of Umbrella.
Algol, the Hero King, is the final boss in the game Soul Calibur IV, and is the creator of Soul Calibur. Algol wields both Soul Edge and Soul calibur . He is also said to hide ten distinct weapons in his body, like a cannon that forms around his hand.
Spider-Man villain often associated with Spider-Slayers, along with his father, Spencer Smythe.
Owner of Tenpenny Tower.
A Doberman who works with Charles F. Muntz in the movie Up.
The primary villain of Tomb Raider: Legend, Amanda was an old friend and archaeology partner to Lara Croft.
Victim of Jigsaw in the Saw franchise. Later she accompanies him in "helping" other people.
Lich from the World of Warcraft universe. He is located inside the dungeon Razorfen Downs.
Sometime Batman villain, sometime anti-hero. Rumored to be the son of The Joker.
Andrew Ryan is the founder of Rapture, the undersea Utopia that is the setting for BioShock. His name is a partial anagram of Ayn Rand, author of the novel Atlas Shrugged, which served as the main inspiration for Ryan's philosophies and aspects of BioShock's story.
Finished long after Dr. Gero's death by his self-aware supercomputer, Android 13 is specifically designed to destroy Goku. He can obtain a greater form once absorbing components from #14 and #15.
Finished long after Dr. Gero's death by his self-aware supercomputer, Android 14 is specifically designed to destroy Goku.
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