@eccentrix: I once vacatioend there and stayed in a hotel 20 meters from that place in Prague! I even visited that medieval torture museum, it was a bad museum.
@hott8bitaction: Yak 3 has it's own story and starts in a new location with some new characters. you'll play as the old hero and you will miss a few references maybe but all in all nr 3 is a good starting point I think.
Firvulag's comments