my vote is gta4 the realism destroyed this game for me. i played all the other gta's and enjoyed all of them but gta4 just wasnt what i wanted and was a chore just to beat.

if the game is good and i enjoyed it yes. i enjoyed uncharted and i have no problem going through it again but if a game like gta4 came out with trophies no i wouldn't play it again because i did not enjoy it. so if i like the game yes if not no.