One of my newest xbox 360 controllers has all but disappeared off the face of the earth. Is it possible to somehow locate controllers that are synced to my xbox?

I don't think so.

It's in your sock drawer

Already checked pretty much everywhere and I'm slowly losing my mind.

I'm not understanding what you're expecting out of your controller.

Are you wondering if your console can locate your remote within a 0.5m radius on a map so that you can find it? Or if your remote can emit noises if you order it to via your console?

I mean that would be really neat, but I'm pretty sure it's not possible. That's some next-gen potential right here though.

Your dog borrowed it for some Halo 4 over at his friends house. Go ask your dog.

It's in the same place where laundry socks disappear to.

Try calling it?

Yell "Xbox,find my fucking Controller!" works every time.