As someone who owns the vive and have done lots with it and seen lots of people do things with it I can give you a basic idea.
Its person to person, whilst your doing roomscale movement with teleporting you are generally fine, the movement is so close to 1 to 1 that the brain doesn't have much issue with it. You can get some disorientation with teleportation but it seems the brain adapts to it pretty quickly.
Free movement (whilst standing) is person to person, whilst sitting its the same. I don't get motion sick but the first time I played Spellfighter VR it hit me pretty hard, the instant I went to move I nearly fell over my body got so confused with what was happening, got very sick not long after lasting for 4 hours. However after doing it again and again in short bursts, it doesn't effect me at all anymore, I don't lose balance nor do I get even slightly sick with free movement.
If you get motion sickness, you're SoL, VR sickness is wierd and hits for a long time when it does hit. However if you don't get it then its still no guarantee, although it seems you can train yourself out of it if you can deal with feeling sick the first few times.
Sadly with VR you can never really tell how each person will react until they try, the only real guarantee I can give is if you already suffer from motion sickness then nothing will change here (without roomscale/teleporting mechanics)
p.s. Frame stuttering, freezing and wierd movement (eg, car flipping upside down) can really hurt your brain, it just doesn't know what to do with the information and shocks you quite a bit.
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