Well, its finally confirmed confirmed (yeah, that's two) that Uncharted 2 is in the works, according to an interview with Christophe Balestra, VP of Naughty Dog, by Jeux France. ReTarDedFisHy, for one, is hella excited that it is double confirmed now, so they're definitely going to do it now. Uncharted was ReTarDedFisHy's game of 2007, because of the surprisingly strong narrative, story and albeit simple, great gameplay mechanics. He can't wait to see footage of U2 in action :D It was already the best looking title of 2007, so Naughty Dog must have something sneaky (despite Naughty being in their name, sheesh) up their sleeves... it's going to look great, we already know that :)

Interested? Here's the link:
http://loot-ninja.com/2008/01/02/uncharted-2-confirmed/