I still have to play Grand Theft Auto 4, Fallout 3, Prince of Persia, a little gem called Project Slypheed, then move on to more recent titles, such as Prototype. All that and I'm still addicted to Street Fighter 4. 
 
For 2010, I have a bunch of pre-orders: Dante's Inferno, Final Fantasy 13, Super Street Fighter 4. Doing it that way gives me some time, and some deadlines, to finish up my backlog of older titles.