Kelswitch

The game is alot of fun mostly by its own standards though, not by Gears 3, MW3 or any other game to come out in last 5 years. 
I'd love to see what the Duke series becomes under Gearbox's direction and a proper structured development cycle. 
Also, wall tits.

That is fucking genius.

HUMOUR

Pretty cool, I actually really like it.

Shame it's ruined by having about a thousand logo's plastered all over it.

Knights Of The Old Republic 
Final Fantasy VIII 
Final Fantasy IX 
Mass Effect 2 
Deus Ex. 
 
Honorable Mentions. 
Dragon Age: Origins (and to a lesser extent, 2) 
Vampire The Masquerade: Bloodlines 
Chrono Trigger 
Persona 3 FES and 4 
Final Fantasy Tactics 

Currently listening to more Darkest Hour, Between The Buried and Me, The Dillinger Escape Plan, Kylesa, Dark Tranquility and Mastodon than I probably should.

Dungeon Keeper 3. 
Syndicate (the Starbreeze rumor game better not just be an fps) 
Jet Set Radio

I'd have been more curious than anything else to see how a traditional Telltale game would play around Scott Pilgrim.. 
Also, movie rocked.