Cartoon Network Punch Time Explosion sounded like a kiddie title to me. A fighting game in the style of Smash Bros. scaled down to release alongside the 3DS. I wasn't interested in the game but I decided to see the character unveils on Gametrailers to hear some familiar voices. I guess I was expecting to hear the same voice actors who played these characters like Phil Lamar (Hermes Conrad on Futurama) as Samurai Jack, or Richard Horvitz (Invader Zim) as Billy, but there are substitutes for almost all of them. 2 out of the 3 Powerpuff Girls are replacements (I don't why having bubbles is a consolation). 
 
I might be making a big deal out of nothing but I'm the kind of guy that notices when Don Cheadle replaced Terrence Howard in Iron Man 2. It's strikes a chord with me when I finally realized some people really claim a role. Quick, who makes a good Batman actor and has reprised his role for so many years?
 
Also, there was a Powerpuff game that was really entertaining on Newgrounds that led me to the webcomic Powerpuff Girls Doujinshi by Bleedman that was also fun read. The  webcomic has a comic book version of the Powerpuff Girls with most of the cast of Cartoon Network.