Please keep in mind, I did not play every game that came out this year. So if there is a character that you feel should be on this list, then it's entirely likely that I did not play their respective games, and thus, know nothing about said character. You are more than welcome to create your own top ten list, I would love to see them. Enjoy! :D
 

10. War (Darksiders) This dude is one of the four horsemen of the Apocalypse, more than enough reason to have him on this list.

9. Chuck Greene (Dead Rising 2) Chuck’s masterful ability to create stuff out of junk is without equal. MacGuyver’s got nothing on Chuck. Truly, there is nothing more effective than a roll of duct tape, at least not with Chuck around.

8. Jorge (Halo: Reach) The stoic and brawny Spartan of the Noble Team, he poses the greatest of threats than all the other members. Him being a Spartan-II means that he wasn’t trained to be mass produced like his Spartan-III partners, he was trained to kill foreign enemies and domestic. Also, he can turn any vehicle into a chain-gun mounted kill machine!

 
6. Mordin Solus (Mass Effect 2) Perhaps the most likable crew member you pick up along in the game. A brilliant scientist and a hell of a singer make this quirky character well deserved to be on this list.

 
5. Alan Wake (Alan Wake) A determined writer who will never stop fighting to save his wife. He’s self-sacrificing and creative. Much like the protagonists of the Silent Hill series, Alan Wake is just a regular guy caught up in irregular situations. Plus who else can use light itself as a weapon?    

 4. Ethan Mars (Heavy Rain) Another regular guy caught in irregular situations is Ethan Mars. A poor father-trying to save his last son from a serial killer, he puts his body through the ringer in this game. He never gives up and will do whatever it takes to save him. Even if it means sacrificing his own life.  

3. Agent Frances York Morgan (Deadly Premonition) One of the most peculiar characters of 2010, you can count on him to get the job done. He’s always willing to help out anyone despite trying to solve a series of gruesome murders. Terrible outfits, unshaven, flies buzzin’ around; doesn’t matter to him he’s got a case to solve.

2. Jim Raynor (Starcraft 2) This is a controversial choice because Jim Raynor did not make his debut this year, but rather back in 1998. To which I say; that was 12 years ago! He hasn’t appeared in another game since, and Starcraft: Ghost doesn’t count. The very likable protagonist of the Starcraft series continues his battle against his betrayers. Often laid back and sarcastic, he’s always willing to do the right thing no matter the cost.

 
1. John Marston (Red Dead Redemption) Probably the most straight forward character, he knows what he wants and he does it. He wants to be with his family and be left alone. Despite all the sin and vice that is bestowed upon him, he is like an unmovable rock and will always remain faithful to his wife. So much shit is dumped on Marston that it’s almost unbelievable that he manages to get out of any of it. John Marston is 2010’s Video Game Man of the year.  

You can check out the Top Ten Video Game Women of 2010 right here.  
You can also check out my own video game blog here as well.