Doing just what the title suggests. I've never written a guide before, so who knows how useful or even readable it might turn out. I have vague ideas and plans for sections, but for now I've just put together an initial bunch of techniques that might be useful to someone. I hope.
Link, in case just going to SpaceChems page is too much effort: http://www.giantbomb.com/guides/spacechem-guide/2236/