Biology battle is a modern dual joystick shooter. It's fast-paced nature and bright colourful pallet often lead to comparisons to Bizarre Creations extremely popular Geometry Wars franchise. It features online leaderboards, Versus, Co-op and 12 "party game" modes for playing with friends.
Biology battle is highly rated when compared to other XNA community games. It has a metacritic score of 69, which is not only better than the majority of community games, but on par with many Xbox Live Arcade games. Some publications have rated the game above 80%. These include GameFocus and Destructoid.