Deadly Premonition has me by the balls. When I started watching the ER, I knew I had found that special game. DP is, in lack of a proper word, grearrible...
 
It's great and terrible at the same time. Great when considering the intentional and unintentional humor, the hysterical animations, the voice acting(I need to find out who the cast is, or I'll go insane) and the crazy plot. Terrible when considering, well, everything else..
 
Having recently bought the game though, I'm finding it hard to prevent myself from watching more ER episodes. Luckily, the focus has shifted to the main plot missions, leaving all of the crazy sidequests for me to discover and complete. If anyone out there has played the game, including the sidequests, can give me a heads up if they are worth the effort it would be much appreciated. Til then, I can hear Zack calling me from my shelf.

Most of the side quests are pretty interesting, and give rewards that are actually useful to you, such as infinite ammo weapons, discounts from stores, improvements to all your cars, or the ability to hold more items/weapons.  If you look at the side mission list on the map, it'll tell you what chapters each is available in, and who the main person involved with the quest is (although, that's not necessarily where it starts, and there are some with prerequisite quests).  Also, don't use the replay chapters option while in chapter 9, as there's a nasty bug where you can lose an essential item and have to start over.