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An affable and friendly Sith Lord who assists the Emperor's Wrath after their betrayal by Darth Baras.
Deathbird is a supervillainess appearing in the Marvel Comics universe. She is part of the Shi'ar race.
An evil alien woman who is the main antagonist of the "Stitch!" anime's third season.
The White Alien Power Ranger.
An alien convict from Dimension X and late-season antagonist in the original Teenage Mutant Ninja Turtles animated series.
Saved from Dodoria by Krillin and Gohan, Dende later has healing powers unlocked, which can cure the wounded like a senzu bean. Later, Dende becomes the guardian of Earth, replacing Kami.
The first of the Decepticon combiners, made up of the six members of the Constructicons.
The main antagonist in Tales of Phantasia. He is a time-traveler from the planet Derris-Kharlan.
A member of the Maximals from the Beast Wars series.
An alien businessman obsessed with money.
A character from "Farscape: The Game" and character from the tv show, Farscape.
A Cabal Centurion in the Destiny series and the main antagonist of the original campaign in Destiny 2. He leads an elite Cabal faction known as the "Red Legion" and aims to steal the Traveler's Light for himself.
Dr. Habbitrale is one of Dr. Jumba Jookiba's rivals and fellow mad scientist. He can be considered an early version of the "Lilo & Stitch" franchise's main antagonist, Dr. Jacques von Hämsterviel.
Dr. Hämsterviel is the main antagonist of Disney's "Lilo & Stitch" franchise after the 2002 original film. The former partner-in-crime of Dr. Jumba Jookiba, this "hamster-like" alien funded the creation of the genetic experiments through shady deals. He strives to take them in order to take over the galaxy, hiring Gantu to do so.
Jumba Jookiba is the alien mad scientist/"evil genius" from the "Lilo & Stitch" franchise. The creator of Stitch and his experiment "cousins", he is actually not really as evil as he likes to claim. His best friend is Pleakley, who he was initially forced to work with. On Earth, he pretends to be Lilo and Nani Pelekai's "uncle".
The Main Antagonist of The Ratchet and Clank series and is the most recurring villain. He hates all organic life and is pro-robotocism alone despite formerly being one. He is the Archenemy of Ratchet,Clank,and Captain Copernicus Qwark.
The main antagonist of the "Lilo & Stitch" Game Boy Advance game. He is a robotic mosquito-like alien mad scientist who has Lilo and various aliens kidnapped to feed them to his army of genetically-modified mosquitos.
Dr. Venom is a recurring antagonist in the Nemesis, Gradius, and Salamander series. He developed the Vic Viper and Metalion, but turned rogue when the Gradius government turned a blind eye to the plights of his people.
The staff Doctor for Planet Express in Futurama.
A fairly significant character in Marvel's cosmic universe. He is also a member of the Guardians of the Galaxy.
A superheroine created for the Supergirl TV series who eventually made it to comics and other media.
Dûl Incaru, the Eternal Return is an Ascendant Hive Wizard and a daughter of Savathûn, the Witch-Queen, serving as the final encounter of The Shattered Throne dungeon.
A character from the MegaMan series. He is an alien robot that was sent to earth to investigate the use of Evil Energy by Dr. Wily.
Dupe, also known as Experiment 344, is one of Stitch's experiment "cousins" in Disney's "Lilo & Stitch" franchise. He is designed to clone individuals into multiples of themselves, although their strength are divided between the clones. He can reverse the cloning to bring the clones back to just the original.
E.T., from the Steven Spielberg movie, is the extra-terrestrial alien who got stranded on Earth and wants to return home. He like Reese's Pieces and has nothing to do with that landfill in New Mexico.
Big Earl is a laid-back, seriously jammin' alien from the planet Funk-o-tron. Although he's totally loyal to his best bud ToeJam and is good to have on your side in a fight, he's not terribly bright, is an absolutely awful driver, and his pants have a habit of falling down.
Ebony Maw was a member of Thanos' Black Order.
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