i5 seems to be everyone's Intel sweet spot at the moment and the i5 3550 is at the mid-upper end of the spectrum. You shouldn't any problems with that. Obviously an i7 will be your best bet for longevity, but it's a pretty steep price increase...so precede with the utmost wallet-caution
Blu-Ray drive? If you absolutely want it, go for it. But that's an easy 80 USD you can deposit into another component (GPU, RAM).
I am a bit of an absolute separatist when it comes to matching CPU/GPU, so your choice of an AMD GPU with an Intel CPU irks me. I've had nasty experiences with cooperation issues when yoking the two together. But I know of plenty of people who disagree with me and go all willy-nilly patchwork, so you are probably safe. The 7850 is an okay choice if gaming at 1920X1080. Even then, juggernauts like Witcher 2 and Battlefield 3 will drop frames (like run somewhere around 40 FPS on high at 1920X1080 with dips to high 20s). I'd either switch over to Nvida 670 (roughly a 100USD more...remember that Blu-Ray we talked about???) or AMD 7950 for more head room.
Be sure to recalculate your power consumption if you make any changes. I personally like to leave myself some room to grow (SLI/CrossFire, additional HDD, SSD), so I placed a 1250W power supply in my current rig.
Hope this helps a bit. I do not profess to keep up with PC tech until about six months before upgrade/new build time, so I'm sure other members of the community will fill in the inevitable gaps I may have left.
Best of luck with the new machine!
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